Repurposing available drugs for neurodevelopmental disorders: The fragile X experience.
Tranfaglia MR, Thibodeaux C, Mason DJ, Brown D, Roberts I, Smith R, Guilliams T, Cogram P.Neuropharmacology. 2019
Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome.
Cogram P, Deacon RMJ, Warner-Schmidt JL, von Schimmelmann MJ, Abrahams BS, During MJ.
Front Behav Neurosci. 2019
Chronic bryostatin-1 rescues Autistic and cognitive phenotypes in the fragile X mice.
Patricia Cogram, Daniel L, Alkon, , David Crockford, , Robert M.J. Deacon, , Michael J Hurley, Miao-Kun Sun and Michael Tranfaglia. Under review
On our pipeline The Naked Mole Rat on a pill. From the thousands of genes we were looking at, we had found the very genes responsible for the highveld mole-rats remarkable age resistance.
Our new anti-ageing drug combination showed signs of improved well being by increasing the expression of DNA protecting genes, involved in the NMR highly effective DNA repair system.
Our study showed that curcumin (C) in combination with cyclodextrin (CD) and N has previously undemonstrated potential as an anti-aging product.
The data was presented at the world’s largest anti-aging conference, Undoing Aging 2019, and a patent has been filed.
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