Lysosomal aberrations in the frontal cortex with age

Evidence for lysosomal aberrations in the frontal cortex with age.

(A) Altered levels of cathepsin D, V-ATPase, Aβ42, ATP13a2 were observed in the brain at 3 years of age compared to 1-year-old O. degus. The blots shown are representative data from an experiment repeated eight times.
(B) Graphs are mean ± SEM brains from brains of eight O. degus for each age group. Significantly different ∗p < 0.01 compared to 1-year-old O. degus.
(C) Table of absolute values mean ± SEM.

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